| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ectonucleoside triphosphate diphosphohydrolase 1 |
|---|
| Ligand | BDBM50276791 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1716384 |
|---|
| IC50 | >300000±n/a nM |
|---|
| Citation |  Kuhrt, D; Ejaz, SA; Afzal, S; Khan, SU; Lecka, J; Sévigny, J; Ehlers, P; Spannenberg, A; Iqbal, J; Langer, P Chemoselective synthesis and biological evaluation of arylated 2-(Trifluoromethyl) quinolines as nucleotide pyrophosphatase (NPPs) inhibitors. Eur J Med Chem138:816-829 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ectonucleoside triphosphate diphosphohydrolase 1 |
|---|
| Name: | Ectonucleoside triphosphate diphosphohydrolase 1 |
|---|
| Synonyms: | CD39 | ENTP1_HUMAN | ENTPD1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 57962.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_612638 |
|---|
| Residue: | 510 |
|---|
| Sequence: | MEDTKESNVKTFCSKNILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHT
SLYIYKWPAEKENDTGVVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQ
HQETPVYLGATAGMRLLRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWI
TINYLLGKFSQKTRWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFR
LYGKDYNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTP
CTKRFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPLQGDFGAF
SAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYIL
SLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFL
MVLFSLVLFTVAIIGLLIFHKPSYFWKDMV
|
|
|
|---|
| BDBM50276791 |
|---|
| n/a |
|---|
| Name | BDBM50276791 |
|---|
| Synonyms: | CHEMBL4164891 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H7BrClF3N2 |
|---|
| Mol. Mass. | 411.603 |
|---|
| SMILES | FC(F)(F)c1nc2c(cccc2c(Cl)c1Br)-c1cccc(c1)C#N |
|---|
| Structure | 
|
|---|
Search and Browse
