| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM321269 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1716891 |
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| Ki | 4.3±n/a nM |
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| Citation |  Donnier-Maréchal, M; Carato, P; Larchanché, PE; Ravez, S; Boulahjar, R; Barczyk, A; Oxombre, B; Vermersch, P; Melnyk, P Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands. Eur J Med Chem138:964-978 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM321269 |
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| n/a |
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| Name | BDBM321269 |
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| Synonyms: | N-[3-(N-methyl-2-phenylethylamino)propyl]-4-chlorobenzamide | US10179761, Compound 3.1.12 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23ClN2O |
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| Mol. Mass. | 330.852 |
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| SMILES | CN(CCCNC(=O)c1ccc(Cl)cc1)CCc1ccccc1 |
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| Structure | 
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