| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM50014946 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1640 |
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| Ki | 1060±n/a nM |
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| Citation |  Ismaiel, AM; Titeler, M; Miller, KJ; Smith, TS; Glennon, RA 5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin. J Med Chem33:755-8 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41920.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells. |
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| Residue: | 377 |
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| Sequence: | MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS
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| BDBM50014946 |
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| n/a |
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| Name | BDBM50014946 |
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| Synonyms: | 2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | 2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine (2-methyl-5-methoxytryptamine) | CHEMBL268800 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H16N2O |
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| Mol. Mass. | 204.2682 |
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| SMILES | COc1ccc2[nH]c(C)c(CCN)c2c1 |
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| Structure | 
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