Reaction Details |
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Target | 5-hydroxytryptamine receptor 2C |
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Ligand | BDBM50014946 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_1859 |
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Ki | 690±n/a nM |
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Citation | Ismaiel, AM; Titeler, M; Miller, KJ; Smith, TS; Glennon, RA 5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin. J Med Chem33:755-8 (1990) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 2C |
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Name: | 5-hydroxytryptamine receptor 2C |
Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
Type: | Enzyme |
Mol. Mass.: | 51935.10 |
Organism: | Rattus norvegicus (Rat) |
Description: | P08909 |
Residue: | 460 |
Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
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BDBM50014946 |
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n/a |
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Name | BDBM50014946 |
Synonyms: | 2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine | 2-(5-Methoxy-2-methyl-1H-indol-3-yl)-ethylamine (2-methyl-5-methoxytryptamine) | CHEMBL268800 |
Type | Small organic molecule |
Emp. Form. | C12H16N2O |
Mol. Mass. | 204.2682 |
SMILES | COc1ccc2[nH]c(C)c(CCN)c2c1 |
Structure |
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