| Reaction Details |
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 | Report a problem with these data |
| Target | Snake venom metalloproteinase neuwiedase |
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| Ligand | BDBM50092158 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1721253 (CHEMBL4136253) |
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| IC50 | 470000±n/a nM |
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| Citation |  Ferreira, FB; Pereira, TM; Souza, DLN; Lopes, DS; Freitas, V; Ávila, VMR; Kümmerle, AE; Sant'Anna, CMR Structure-Based Discovery of Thiosemicarbazone Metalloproteinase Inhibitors for Hemorrhage Treatment in Snakebites. ACS Med Chem Lett8:1136-1141 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Snake venom metalloproteinase neuwiedase |
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| Name: | Snake venom metalloproteinase neuwiedase |
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| Synonyms: | 3.4.24.- | SVMP | Snake venom metalloproteinase neuwiedase | VM1N_BOTPA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22528.77 |
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| Organism: | Bothrops pauloensis |
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| Description: | ChEMBL_118198 |
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| Residue: | 198 |
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| Sequence: | QQRFFPQRYIELVIVADRRMYTKYNSDSNKIRTRVHELVNTVNGFFRSMNVDASLANLEV
WSKKDLIKVEKDSSKTLTSFGEWRERDLLRRKSHDNAQLLTAIDFNGNTIGRAYLGSMCN
PKRSVGIVQDHSPINLLVGVTMAHELGHNLGMEHDGKDCLCGASLCIMSPGLTDGPSYEF
SDCSKDYYQTFLTNHNPQ
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| BDBM50092158 |
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| n/a |
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| Name | BDBM50092158 |
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| Synonyms: | 1,10-phenanthroline | CHEMBL415879 | US10669227, Compound 1,10-phenanthroline | US11608309, Compound 1,10-phenanthroline | US9187406, 1,10-phenanthroline | cid_1318 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8N2 |
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| Mol. Mass. | 180.2053 |
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| SMILES | c1cnc2c(c1)ccc1cccnc21 |
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| Structure | 
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