| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone acetyltransferase KAT2B |
|---|
| Ligand | BDBM50282619 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1724426 (CHEMBL4139704) |
|---|
| IC50 | 7100±n/a nM |
|---|
| Citation |  Wapenaar, H; van den Bosch, T; Leus, NGJ; van der Wouden, PE; Eleftheriadis, N; Hermans, J; Hailu, GS; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, HJ; Dekker, FJ The relevance of K Eur J Med Chem136:480-486 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone acetyltransferase KAT2B |
|---|
| Name: | Histone acetyltransferase KAT2B |
|---|
| Synonyms: | Histone acetyltransferase KAT2A/KAT2B | Histone acetyltransferase PCAF | KAT2B | KAT2B_HUMAN | PCAF |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 93045.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1502838 |
|---|
| Residue: | 832 |
|---|
| Sequence: | MSEAGGAGPGGCGAGAGAGAGPGALPPQPAALPPAPPQGSPCAAAAGGSGACGPATAVAA
AGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTP
PRADLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEED
ADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKE
RQTIVELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPR
YETTQVFGRTLLRSVFTVMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQ
NSPIWDQDFLSASSRTSQLGIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSG
LEANPGEKRKMTDSHVLEEAKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSA
RDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFD
PKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH
DILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFS
VIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSK
EPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNR
YYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSKIKEAGLIDK
|
|
|
|---|
| BDBM50282619 |
|---|
| n/a |
|---|
| Name | BDBM50282619 |
|---|
| Synonyms: | CHEMBL4159902 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H8N2O |
|---|
| Mol. Mass. | 160.1726 |
|---|
| SMILES | Nc1ccc(O)c2ccncc12 |
|---|
| Structure | 
|
|---|
Search and Browse
