| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT8 |
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| Ligand | BDBM43339 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1724430 (CHEMBL4139708) |
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| IC50 | 1800±n/a nM |
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| Citation |  Wapenaar, H; van den Bosch, T; Leus, NGJ; van der Wouden, PE; Eleftheriadis, N; Hermans, J; Hailu, GS; Rotili, D; Mai, A; Dömling, A; Bischoff, R; Haisma, HJ; Dekker, FJ The relevance of K Eur J Med Chem136:480-486 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT8 |
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| Name: | Histone acetyltransferase KAT8 |
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| Synonyms: | KAT8 | KAT8_HUMAN | Lysine acetyltransferase 8 | MOF | MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 | MYST-1 | MYST1 | hMOF |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52413.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_796800 |
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| Residue: | 458 |
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| Sequence: | MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
LVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
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| BDBM43339 |
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| n/a |
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| Name | BDBM43339 |
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| Synonyms: | 4-amino-1-naphthalenol;hydrochloride | 4-amino-1-naphthol;hydrochloride | 4-aminonaphthalen-1-ol;hydrochloride | 4-azanylnaphthalen-1-ol;hydrochloride | CHEMBL576321 | PC-0685415 | PCMD-CC-PAB-253 | cid_2723858 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H9NO |
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| Mol. Mass. | 159.1846 |
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| SMILES | Nc1ccc(O)c2ccccc12 |
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| Structure | 
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