| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50016312 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_214691 (CHEMBL817654) |
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| Kd | 10±n/a nM |
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| Citation |  Grzonka, Z; Kasprzykowski, F; Kojro, E; Darlak, K; Melin, P; Fahrenholz, F; Crause, P; Boer, R Arginine-vasopressin analogues with high antidiuretic/vasopressor selectivity. Synthesis, biological activity, and receptor binding affinity of arginine-vasopressin analogues with substitutions in positions 1, 2, 4, 7, and 8. J Med Chem29:96-9 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | AVPR2 | V2R_BOVIN | VASOPRESSIN V2 | Vasopressin V2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40248.83 |
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| Organism: | BOVINE |
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| Description: | VASOPRESSIN V2 AVPR2 BOVINE::P48044 |
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| Residue: | 370 |
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| Sequence: | MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLG
ALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQ
RDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPV
PRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATA
SSFLAKDTPS
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| BDBM50016312 |
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| n/a |
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| Name | BDBM50016312 |
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| Synonyms: | CHEMBL265119 | [Sar7D-Arg8]VP (Vasopressin ) |
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| Type | Small organic molecule |
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| Emp. Form. | C44H63N15O12S2 |
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| Mol. Mass. | 1058.194 |
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| SMILES | CN(CC(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O)C(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1 |
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| Structure | 
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