| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
|---|
| Ligand | BDBM50016317 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_214690 |
|---|
| Kd | 8.50±n/a nM |
|---|
| Citation |  Grzonka, Z; Kasprzykowski, F; Kojro, E; Darlak, K; Melin, P; Fahrenholz, F; Crause, P; Boer, R Arginine-vasopressin analogues with high antidiuretic/vasopressor selectivity. Synthesis, biological activity, and receptor binding affinity of arginine-vasopressin analogues with substitutions in positions 1, 2, 4, 7, and 8. J Med Chem29:96-9 (1986) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vasopressin V2 receptor |
|---|
| Name: | Vasopressin V2 receptor |
|---|
| Synonyms: | AVPR2 | V2R_BOVIN | VASOPRESSIN V2 | Vasopressin V2 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40248.83 |
|---|
| Organism: | BOVINE |
|---|
| Description: | VASOPRESSIN V2 AVPR2 BOVINE::P48044 |
|---|
| Residue: | 370 |
|---|
| Sequence: | MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLG
ALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQ
RDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPV
PRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAP
REGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATA
SSFLAKDTPS
|
|
|
|---|
| BDBM50016317 |
|---|
| n/a |
|---|
| Name | BDBM50016317 |
|---|
| Synonyms: | CHEMBL2371674 | [Mpa1Val4MeAla7]AVP (Arginine-vasopressin ) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C45H65N13O11S2 |
|---|
| Mol. Mass. | 1028.208 |
|---|
| SMILES | [#6]-[#6](-[#6])-[#6@H]-1-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6](=O)-[#6]-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6]-1=O)-[#6](=O)-[#7](-[#6])-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O |
|---|
| Structure | 
|
|---|
Search and Browse
