| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50016778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_58203 |
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| Ki | 5.2±n/a nM |
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| Citation |  Harrold, MW; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD Synthesis and D2 dopaminergic activity of pyrrolidinium, tetrahydrothiophenium, and tetrahydrothiophene analogues of sulpiride. J Med Chem32:874-80 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 50957.64 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P61168 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50016778 |
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| n/a |
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| Name | BDBM50016778 |
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| Synonyms: | 1-Ethyl-2-[(2-methoxy-5-sulfamoyl-benzoylamino)-methyl]-tetrahydro-thiophenium; iodide | CHEMBL170622 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H23N2O4S2 |
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| Mol. Mass. | 359.484 |
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| SMILES | CC[S+]1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O |
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| Structure | 
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