| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
|---|
| Ligand | BDBM50016888 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_33027 |
|---|
| IC50 | 559.0±n/a nM |
|---|
| Citation |  Hutchison, A; Williams, M; de Jesus, R; Stone, GA; Sylvester, L; Clarke, FH; Sills, MA 2H-[1]benzopyrano[3,4-b]pyridines: synthesis and activity at central monoamine receptors. J Med Chem32:720-7 (1989) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-2A adrenergic receptor |
|---|
| Name: | Alpha-2A adrenergic receptor |
|---|
| Synonyms: | ADA2A_BOVIN | ADRA2A | Alpha-2A adrenergic receptor | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2D adrenergic receptor | Alpha-2Da adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha2A | adrenergic Alpha2D |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49275.13 |
|---|
| Organism: | BOVINE |
|---|
| Description: | adrenergic Alpha2 0 BOVINE::Q28838 |
|---|
| Residue: | 452 |
|---|
| Sequence: | MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSG
QPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATA
AELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSS
EHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAK
ASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCN
SSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
|
|
|---|
| BDBM50016888 |
|---|
| n/a |
|---|
| Name | BDBM50016888 |
|---|
| Synonyms: | 1-Propyl-2,3,4,4a,10,10a-hexahydro-1H-9-oxa-1-aza-phenanthren-6-ol | CHEMBL162955 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H21NO2 |
|---|
| Mol. Mass. | 247.3327 |
|---|
| SMILES | CCCN1CCC[C@H]2[C@H]1COc1ccc(O)cc21 |
|---|
| Structure | 
|
|---|
Search and Browse
