| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50449648 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1740326 (CHEMBL4156076) |
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| IC50 | 0.036000±n/a nM |
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| Citation |  Varano, F; Catarzi, D; Vincenzi, F; Falsini, M; Pasquini, S; Borea, PA; Colotta, V; Varani, K Structure-activity relationship studies and pharmacological characterization of N Eur J Med Chem155:552-561 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50449648 |
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| n/a |
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| Name | BDBM50449648 |
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| Synonyms: | CHEMBL4161758 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11N5OS2 |
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| Mol. Mass. | 329.4 |
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| SMILES | Nc1nc(NCc2cccs2)nc2sc(nc12)-c1ccco1 |
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| Structure | 
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