| Reaction Details |
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 | Report a problem with these data |
| Target | Thiosulfate sulfurtransferase |
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| Ligand | BDBM50450012 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1741629 (CHEMBL4157379) |
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| IC50 | 53000±n/a nM |
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| Citation |  Abdeen, S; Kunkle, T; Salim, N; Ray, AM; Mammadova, N; Summers, C; Stevens, M; Ambrose, AJ; Park, Y; Schultz, PG; Horwich, AL; Hoang, QQ; Chapman, E; Johnson, SM Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA). J Med Chem61:7345-7357 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thiosulfate sulfurtransferase |
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| Name: | Thiosulfate sulfurtransferase |
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| Synonyms: | 2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33432.06 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118080 |
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| Residue: | 297 |
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| Sequence: | MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
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| BDBM50450012 |
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| n/a |
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| Name | BDBM50450012 |
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| Synonyms: | CHEMBL4167333 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H14Cl2N4O7S3 |
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| Mol. Mass. | 625.481 |
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| SMILES | [O-][N+](=O)c1cc(ccc1Cl)S(=O)(=O)Nc1ccc(cc1)-c1nc2cc(NS(=O)(=O)c3ccc(Cl)s3)ccc2o1 |
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| Structure | 
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