| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50451272 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1744757 (CHEMBL4179267) |
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| Ki | 490±n/a nM |
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| Citation |  Enkhtaivan, G; Muthuraman, P; Kim, DH; Mistry, B Discovery of berberine based derivatives as anti-influenza agent through blocking of neuraminidase. Bioorg Med Chem25:5185-5193 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | Influenza A Virus Neuraminidase | NA | NRAM_I34A1 | Neuraminidase | Neuraminidase A |
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| Type: | Enzyme |
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| Mol. Mass.: | 50124.14 |
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| Organism: | Influenza A virus (A/Puerto Rico/8/34/Mount Sinai(H1N1)) |
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| Description: | P03468 |
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| Residue: | 454 |
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| Sequence: | MNPNQKIITIGSICLVVGLISLILQIGNIISIWISHSIQTGSQNHTGICNQNIITYKNST
WVKDTTSVILTGNSSLCPIRGWAIYSKDNSIRIGSKGDVFVIREPFISCSHLECRTFFLT
QGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGI
SGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECACVNGSCFTIMTDGPSDGLASYKI
FKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIG
YICSGVFGDNPRPEDGTGSCGPVYVDGANGVKGFSYRYGNGVWIGRTKSHSSRHGFEMIW
DPNGWTETDSKFSVRQDVVAMTDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPKEKT
IWTSASSISFCGVNSDTVDWSWPDGAELPFSIDK
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| BDBM50451272 |
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| n/a |
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| Name | BDBM50451272 |
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| Synonyms: | CHEMBL4212505 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H25ClN2O4 |
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| Mol. Mass. | 537.005 |
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| SMILES | [Cl-].COc1cc(Cn2c3ccccc3c3ccccc23)c2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1O |
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| Structure | 
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