| Reaction Details |
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 | Report a problem with these data |
| Target | Chitotriosidase-1 |
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| Ligand | BDBM50453494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1750198 (CHEMBL4184958) |
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| IC50 | 175±n/a nM |
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| Citation |  TBA Bioorg Med Chem Lett28:310-314 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitotriosidase-1 |
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| Name: | Chitotriosidase-1 |
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| Synonyms: | 3.2.1.14 | CHIT1_MOUSE | Chit1 | Chitinase-1 | Chitotriosidase-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51108.04 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_117450 |
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| Residue: | 464 |
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| Sequence: | MVQSLAWAGVMTLLMVQWGSAAKLVCYLTNWSQYRTEAVRFFPRDVDPNLCTHVIFAFAG
MDNHQLSTVEHNDELLYQELNSLKTKNPKLKTLLAVGGWTFGTQKFTDMVATASNRQTFV
KSALSFLRTQGFDGLDLDWEFPGGRGSPTVDKERFTALIQDLAKAFQEEAQSSGKERLLL
TAAVPSDRGLVDAGYEVDKIAQSLDFINLMAYDFHSSLEKTTGHNSPLYKRQGESGAAAE
QNVDAAVTLWLQKGTPASKLILGMPTYGRSFTLASSSDNGVGAPATGPGAPGPYTKDKGV
LAYYEACSWKERHRIEDQKVPYAFQDNQWVSFDDVESFKAKAAYLKQKGLGGAMVWVLDL
DDFKGSFCNQGPYPLIRTLRQELNLPSETPRSPEQIIPEPRPSSMPEQGPSPGLDNFCQG
KADGVYPNPGDESTYYNCGGGRLFQQSCPPGLVFRASCKCCTWS
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| BDBM50453494 |
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| n/a |
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| Name | BDBM50453494 |
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| Synonyms: | CHEMBL4210195 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H30ClN7O |
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| Mol. Mass. | 419.952 |
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| SMILES | CN1C[C@H](Cc2ccc(Cl)cc2)N(C[C@@H]1CO)C1CCN(CC1)c1n[nH]c(N)n1 |r| |
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| Structure | 
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