| Reaction Details |
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 | Report a problem with these data |
| Target | Amiloride-sensitive amine oxidase [copper-containing] |
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| Ligand | BDBM50020274 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_53889 |
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| Ki | 2700±n/a nM |
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| Citation |  Kendrick, DA; Danzin, C; Kolb, M 2,2-Difluoro-5-hexyne-1,4-diamine: a potent enzyme-activated inhibitor of ornithine decarboxylase. J Med Chem32:170-3 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Amiloride-sensitive amine oxidase [copper-containing] |
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| Name: | Amiloride-sensitive amine oxidase [copper-containing] |
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| Synonyms: | ABP | ABP1 | AOC1 | AOC1_HUMAN | Amiloride-binding protein | DAO | DAO1 | Diamine oxidase | Diamine oxidase (DAO) | Histaminase | KAO | Kidney amine oxidase |
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| Type: | Protein |
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| Mol. Mass.: | 85387.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P19801 |
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| Residue: | 751 |
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| Sequence: | MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS
TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP
GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR
CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG
KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP
RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG
GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE
MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH
ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT
NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM
ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI
ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD
NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
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| BDBM50020274 |
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| n/a |
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| Name | BDBM50020274 |
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| Synonyms: | 2,2-Difluoro-hex-5-yne-1,4-diamonium; dichloride | CHEMBL47011 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H12F2N2 |
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| Mol. Mass. | 150.1686 |
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| SMILES | [NH3+]CC(F)(F)CC([NH3+])C#C |
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| Structure | 
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