| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
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| Ligand | BDBM50005265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1788 (CHEMBL616762) |
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| Ki | 2070±n/a nM |
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| Citation |  Glennon, RA; Titeler, M; Lyon, RA; Slusher, RM N,N-di-n-propylserotonin: binding at serotonin binding sites and a comparison with 8-hydroxy-2-(di-n-propylamino)tetralin. J Med Chem31:867-70 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1B |
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| Name: | 5-hydroxytryptamine receptor 1B |
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| Synonyms: | 5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B |
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| Type: | Protein |
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| Mol. Mass.: | 43173.33 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P28564 |
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| Residue: | 386 |
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| Sequence: | MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATT
LSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDF
WLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPP
FFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTP
NKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKL
MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLI
NPIIYTMSNEDFKQAFHKLIRFKCTG
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| BDBM50005265 |
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| n/a |
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| Name | BDBM50005265 |
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| Synonyms: | (+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine | (-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine | (Rec)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine; compound with 2-(2,5-dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine | 2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine | 2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine((R)-(-)-DOM) | 2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-ethylamine(DOM) | CHEMBL8600 | DOM | DOM,R(-) | Racemic DOM |
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| Type | Small organic molecule |
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| Emp. Form. | C12H19NO2 |
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| Mol. Mass. | 209.2848 |
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| SMILES | COc1cc(CC(C)N)c(OC)cc1C |
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| Structure | 
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