| Reaction Details |
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 | Report a problem with these data |
| Target | cAMP-dependent protein kinase type II-beta regulatory subunit |
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| Ligand | BDBM50455159 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1753987 (CHEMBL4188747) |
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| Kd | 557±n/a nM |
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| Citation |  Bendzunas, NG; Dörfler, S; Autenrieth, K; Bertinetti, D; Machal, EMF; Kennedy, EJ; Herberg, FW Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2. Bioorg Med Chem26:1174-1178 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| cAMP-dependent protein kinase type II-beta regulatory subunit |
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| Name: | cAMP-dependent protein kinase type II-beta regulatory subunit |
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| Synonyms: | KAP3_HUMAN | PRKAR2B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46282.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_11972 |
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| Residue: | 418 |
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| Sequence: | MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGD
LGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAY
NPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEH
VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATS
PGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDG
EQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKP
RAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
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| BDBM50455159 |
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| n/a |
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| Name | BDBM50455159 |
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| Synonyms: | CHEMBL4205523 |
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| Type | Small organic molecule |
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| Emp. Form. | C99H175N23O23 |
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| Mol. Mass. | 2055.5891 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCOCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@]1(C)CCC\C=C\CCC[C@](C)(NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(O)=O |r,t:92| |
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| Structure | 
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