| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 17 |
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| Ligand | BDBM25525 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1756644 (CHEMBL4191652) |
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| IC50 | >100000±n/a nM |
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| Citation |  Bodle, CR; Mackie, DI; Hayes, MP; Schamp, JH; Miller, MR; Henry, MD; Doorn, JA; Houtman, JCD; James, MA; Roman, DL Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines. J Nat Prod80:1992-2000 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Regulator of G-protein signaling 17 |
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| Name: | Regulator of G-protein signaling 17 |
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| Synonyms: | RGS17 | RGS17_HUMAN | RGSZ2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 24356.71 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118219 |
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| Residue: | 210 |
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| Sequence: | MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTK
MESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDL
KKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYT
LMHRDSFPRFLNSQIYKSFVESTAGSSSES
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| BDBM25525 |
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| n/a |
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| Name | BDBM25525 |
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| Synonyms: | 24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^{2,10}.0^{4,8}.0^{14,22}.0^{17,21}]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21),23-nonaen-24-ium | CHEMBL490129 | Pseudochelerythrine | Veadent | cid_5154 | sanguinarine | sangvinarin |
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| Type | Small organic molecule |
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| Emp. Form. | C20H14NO4 |
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| Mol. Mass. | 332.3289 |
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| SMILES | C[n+]1cc2c3OCOc3ccc2c2ccc3cc4OCOc4cc3c12 |
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| Structure | 
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