| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-galactosidase |
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| Ligand | BDBM50456590 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1757467 (CHEMBL4192475) |
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| IC50 | 173000±n/a nM |
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| Citation |  Martínez-Bailén, M; Carmona, AT; Moreno-Clavijo, E; Robina, I; Ide, D; Kato, A; Moreno-Vargas, AJ Tuning of ?-glucosidase and ?-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules. Eur J Med Chem138:532-542 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-galactosidase |
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| Name: | Beta-galactosidase |
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| Synonyms: | β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1 |
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| Type: | Protein |
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| Mol. Mass.: | 73420.88 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | n/a |
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| Residue: | 653 |
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| Sequence: | MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVP
RFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILR
PGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPII
TVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVD
FSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGA
NVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVP
EGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTM
LPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMG
RVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAH
SPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTL
FVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
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| BDBM50456590 |
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| n/a |
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| Name | BDBM50456590 |
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| Synonyms: | CHEMBL4206239 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H16N4O2 |
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| Mol. Mass. | 260.2917 |
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| SMILES | O[C@@H]1CN[C@H](Cn2cc(nn2)-c2ccccc2)[C@@H]1O |r| |
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| Structure | 
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