| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
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| Ligand | BDBM50456848 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1758331 (CHEMBL4193339) |
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| Ki | 1.1±n/a nM |
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| Citation |  Sakauchi, N; Furukawa, H; Shirai, J; Sato, A; Kuno, H; Saikawa, R; Yoshida, M Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective ? Eur J Med Chem139:114-127 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-1D adrenergic receptor |
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| Name: | Alpha-1D adrenergic receptor |
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| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 60485.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
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| Residue: | 572 |
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| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
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| BDBM50456848 |
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| n/a |
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| Name | BDBM50456848 |
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| Synonyms: | CHEMBL4208816 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14Cl3N3OS |
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| Mol. Mass. | 378.704 |
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| SMILES | Cl.CSc1ccc(Cl)cc1Cn1cc(Cl)cc(C(N)=O)c1=N |
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| Structure | 
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