| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
|---|
| Ligand | BDBM50021521 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_151701 |
|---|
| IC50 | 200±n/a nM |
|---|
| Citation |  Biftu, T; Gamble, NF; Doebber, T; Hwang, SB; Shen, TY; Snyder, J; Springer, JP; Stevenson, R Conformation and activity of tetrahydrofuran lignans and analogues as specific platelet activating factor antagonists. J Med Chem29:1917-21 (1986) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Platelet-activating factor receptor |
|---|
| Name: | Platelet-activating factor receptor |
|---|
| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 39005.63 |
|---|
| Organism: | Cavia porcellus |
|---|
| Description: | n/a |
|---|
| Residue: | 342 |
|---|
| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
|
|
|
|---|
| BDBM50021521 |
|---|
| n/a |
|---|
| Name | BDBM50021521 |
|---|
| Synonyms: | 2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan | CHEMBL56856 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H28O5 |
|---|
| Mol. Mass. | 372.4547 |
|---|
| SMILES | COc1ccc(cc1OC)C1O[C@H]([C@@H](C)[C@H]1C)c1ccc(OC)c(OC)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
