| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamyl aminopeptidase |
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| Ligand | BDBM50457465 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1759817 (CHEMBL4194825) |
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| Ki | 130±n/a nM |
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| Citation |  Amin, SA; Adhikari, N; Jha, T Design of Aminopeptidase N Inhibitors as Anti-cancer Agents. J Med Chem61:6468-6490 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamyl aminopeptidase |
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| Name: | Glutamyl aminopeptidase |
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| Synonyms: | AMPE_HUMAN | AP-A | Aminopeptidase A | CD_antigen=CD249 | Differentiation antigen gp160 | EAP | ENPEP | Glutamyl aminopeptidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 109226.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_32829 |
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| Residue: | 957 |
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| Sequence: | MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHL
PSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVS
ISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPS
SGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKK
ATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRI
SNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAME
NWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFAS
FFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYS
KGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTR
QMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSE
KEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLID
DAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYF
QGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPV
NLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLK
DTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFN
TELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG
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| BDBM50457465 |
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| n/a |
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| Name | BDBM50457465 |
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| Synonyms: | CHEMBL4204736 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29N2O5P |
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| Mol. Mass. | 432.4498 |
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| SMILES | CC(N)P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@](C)(Cc1ccccc1)C(O)=O |r| |
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| Structure | 
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