| Reaction Details |
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 | Report a problem with these data |
| Target | Aminopeptidase B |
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| Ligand | BDBM50457479 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1759799 (CHEMBL4194807) |
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| Ki | 1000±n/a nM |
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| Citation |  Amin, SA; Adhikari, N; Jha, T Design of Aminopeptidase N Inhibitors as Anti-cancer Agents. J Med Chem61:6468-6490 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aminopeptidase B |
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| Name: | Aminopeptidase B |
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| Synonyms: | AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep |
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| Type: | PROTEIN |
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| Mol. Mass.: | 72609.93 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1344423 |
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| Residue: | 650 |
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| Sequence: | MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLN
GKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQ
ALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFP
CFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLAS
AEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGM
ENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRIST
ILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCF
VSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFN
RWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLD
KILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGK
QKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
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| BDBM50457479 |
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| n/a |
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| Name | BDBM50457479 |
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| Synonyms: | CHEMBL1159812 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H13NS2 |
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| Mol. Mass. | 151.293 |
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| SMILES | CSCCC(N)CS |
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| Structure | 
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