| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 11B1, mitochondrial |
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| Ligand | BDBM50022117 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_194 |
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| IC50 | 10000±n/a nM |
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| Citation |  Cross, PE; Dickinson, RP; Parry, MJ; Randall, MJ Selective thromboxane synthetase inhibitors. 2. 3-(1H-imidazol-1-ylmethyl)-2-methyl-1H-indole-1-propanoic acid and analogues. J Med Chem29:342-6 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 11B1, mitochondrial |
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| Name: | Cytochrome P450 11B1, mitochondrial |
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| Synonyms: | C11B1_RAT | Cyp11b-1 | Cyp11b1 | Cytochrome P450 11B | Cytochrome P450 11B1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57478.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1475489 |
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| Residue: | 499 |
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| Sequence: | MALRVTADVWLARPWQCLHRTRALGTTAKVAPKTLKPFEAIPQYSRNKWLKMIQILREQG
QENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPHRMPLEPWVAHR
ELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENV
HGSMSINIQSNMFNYTMEASHFVISGERLGLTGHDLKPESVTFTHALHSMFKSTTQLMFL
PKSLTRWTSTRVWKEHFDSWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSM
DAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIVANPQKAMSD
LPLLRAALKETLRLYPVGSFVERIVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVFPRPE
RYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDMQMV
FRFLLMPSSSPFLTFRPVS
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| BDBM50022117 |
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| n/a |
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| Name | BDBM50022117 |
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| Synonyms: | 1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL115899 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15N3 |
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| Mol. Mass. | 225.289 |
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| SMILES | CCn1cc(Cn2ccnc2)c2ccccc12 |
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| Structure | 
|
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