| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase omega-1 |
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| Ligand | BDBM50370232 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1764008 (CHEMBL4199255) |
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| IC50 | 75000±n/a nM |
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| Citation |  Xie, Y; Dahlin, JL; Oakley, AJ; Casarotto, MG; Board, PG; Baell, JB Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem61:7448-7470 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase omega-1 |
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| Name: | Glutathione S-transferase omega-1 |
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| Synonyms: | GSTO 1-1 | GSTO1 | GSTO1_HUMAN | GSTTLP28 | Glutathione S-transferase omega-1 | Glutathione transferase omega 1 | glutathione S-transferase omega-1 isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27565.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_11172 |
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| Residue: | 241 |
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| Sequence: | MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKP
EWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELF
SKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPW
FERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYG
L
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| BDBM50370232 |
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| n/a |
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| Name | BDBM50370232 |
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| Synonyms: | BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampicin |
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| Type | Small organic molecule |
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| Emp. Form. | C43H58N4O12 |
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| Mol. Mass. | 822.9402 |
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| SMILES | CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |r,c:33,t:3,35| |
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| Structure | 
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