Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM50095997 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1764054 (CHEMBL4199301) |
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IC50 | 38±n/a nM |
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Citation | Trivedi-Parmar, V; Jorgensen, WL Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor. J Med Chem61:8104-8119 (2018) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
Type: | Enzyme |
Mol. Mass.: | 12478.18 |
Organism: | Homo sapiens (Human) |
Description: | P14174 |
Residue: | 115 |
Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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BDBM50095997 |
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n/a |
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Name | BDBM50095997 |
Synonyms: | 3',4',7-trihydroxyisoflavone | CHEMBL13486 |
Type | Small organic molecule |
Emp. Form. | C15H10O5 |
Mol. Mass. | 270.2369 |
SMILES | Oc1ccc2c(c1)occ(-c1ccc(O)c(O)c1)c2=O |
Structure |
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