Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM31712 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1764058 (CHEMBL4199305) |
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Ki | 5550±n/a nM |
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Citation | Trivedi-Parmar, V; Jorgensen, WL Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor. J Med Chem61:8104-8119 (2018) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
Type: | Enzyme |
Mol. Mass.: | 12478.18 |
Organism: | Homo sapiens (Human) |
Description: | P14174 |
Residue: | 115 |
Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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BDBM31712 |
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n/a |
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Name | BDBM31712 |
Synonyms: | HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 | SMR000058356 | cid_3598 |
Type | Small organic molecule |
Emp. Form. | C13H6Cl6O2 |
Mol. Mass. | 406.904 |
SMILES | Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl |
Structure |
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