Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMacrophage migration inhibitory factor
LigandBDBM31712
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1764058 (CHEMBL4199305)
Ki 5550±n/a nM
Citation Trivedi-Parmar, VJorgensen, WL Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor. J Med Chem61:8104-8119 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Macrophage migration inhibitory factor
Name:Macrophage migration inhibitory factor
Synonyms:GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:Enzyme
Mol. Mass.:12478.18
Organism:Homo sapiens (Human)
Description:P14174
Residue:115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM31712
n/a
NameBDBM31712
Synonyms:HEXACHLOROPHENE | Hexach-lorophene | MLS000028433 | SMR000058356 | cid_3598
TypeSmall organic molecule
Emp. Form.C13H6Cl6O2
Mol. Mass.406.904
SMILESOc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: