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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase Tec | ||
| Ligand | BDBM50458604 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1764259 (CHEMBL4199506) | ||
| IC50 | 0.110000±n/a nM | ||
| Citation |  Blass, BE Covalent Inhibitors of the TEC Family of Kinases and Their Methods of Use. ACS Med Chem Lett9:587-589 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase Tec | |||
| Name: | Tyrosine-protein kinase Tec | ||
| Synonyms: | PSCTK4 | TEC | TEC_HUMAN | Tyrosine-protein kinase TEC (TEC) | ||
| Type: | Protein | ||
| Mol. Mass.: | 73597.00 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 631 | ||
| Sequence: |
| ||
| BDBM50458604 | |||
| n/a | |||
| Name | BDBM50458604 | ||
| Synonyms: | CHEMBL4214683 | US10752615, Compound 149 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H26N6O2S | ||
| Mol. Mass. | 498.599 | ||
| SMILES | Cc1nccc(n1)-c1ccc(s1)C(=O)Nc1nc2ccccc2n1[C@H]1C[C@]2(C1)CCN(C2)C(=O)C=C |r,wU:26.32,24.27,(71.14,-29.4,;69.74,-30.04,;69.6,-31.58,;68.2,-32.22,;66.94,-31.32,;67.1,-29.79,;68.49,-29.15,;65.84,-28.9,;65.83,-27.36,;64.37,-26.9,;63.48,-28.16,;64.39,-29.38,;61.95,-28.17,;61.17,-26.84,;61.18,-29.51,;59.64,-29.52,;58.73,-28.27,;57.25,-28.76,;55.92,-27.99,;54.59,-28.76,;54.59,-30.31,;55.92,-31.08,;57.26,-30.31,;58.74,-30.78,;59.22,-32.24,;60.6,-32.93,;59.9,-34.31,;58.53,-33.61,;61.4,-34.64,;61.56,-36.17,;60.15,-36.79,;59.12,-35.64,;59.82,-38.29,;60.96,-39.33,;58.35,-38.76,;58.02,-40.26,)| | ||
| Structure | 
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