| Reaction Details |
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 | Report a problem with these data |
| Target | Albumin |
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| Ligand | BDBM50197883 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1765445 (CHEMBL4200692) |
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| Kd | 2500±n/a nM |
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| Citation |  Miller, M; Pal, A; Albusairi, W; Joo, H; Pappas, B; Haque Tuhin, MT; Liang, D; Jampala, R; Liu, F; Khan, J; Faaij, M; Park, M; Chan, W; Graef, I; Zamboni, R; Kumar, N; Fox, J; Sinha, U; Alhamadsheh, M Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis. J Med Chem61:7862-7876 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Albumin |
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| Name: | Albumin |
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| Synonyms: | ALB | ALBU_HUMAN | Serum albumin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69362.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1509401 |
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| Residue: | 609 |
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| Sequence: | MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPF
EDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEP
ERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLF
FAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAV
ARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK
ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYAR
RHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE
QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVV
LNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTL
SEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLV
AASQAALGL
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| BDBM50197883 |
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| n/a |
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| Name | BDBM50197883 |
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| Synonyms: | CHEBI:78538 | FX-1006 | Tafamidis | US10377729, Compound Tafamidis | Vyndaqel |
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| Type | Small organic molecule |
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| Emp. Form. | C14H7Cl2NO3 |
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| Mol. Mass. | 308.116 |
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| SMILES | OC(=O)c1ccc2nc(oc2c1)-c1cc(Cl)cc(Cl)c1 |
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| Structure | 
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