| Reaction Details |
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 | Report a problem with these data |
| Target | Butyrophilin subfamily 3 member A1 |
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| Ligand | BDBM50459335 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1766273 (CHEMBL4201520) |
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| EC50 | 62±n/a nM |
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| Citation |  Lentini, NA; Foust, BJ; Hsiao, CC; Wiemer, AJ; Wiemer, DF Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent V?9 V?2 T Cell Stimulation. J Med Chem61:8658-8669 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Butyrophilin subfamily 3 member A1 |
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| Name: | Butyrophilin subfamily 3 member A1 |
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| Synonyms: | BT3A1_HUMAN | BTF5 | BTN3A1 | Butyrophilin subfamily 3 member A1 | CD_antigen=CD277 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57685.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_117363 |
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| Residue: | 513 |
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| Sequence: | MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSA
ETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASD
SGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWS
NNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADP
FFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQ
EQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQR
SVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKG
WVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGS
HIHTFLDVSFSEALYPVFRILTLEPTALTICPA
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| BDBM50459335 |
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| n/a |
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| Name | BDBM50459335 |
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| Synonyms: | CHEMBL4215122 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H26NO5P |
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| Mol. Mass. | 391.3979 |
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| SMILES | CCOC(=O)CNP(=O)(CC\C=C(/C)CO)Oc1cccc2ccccc12 |
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| Structure | 
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