| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin receptor type A |
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| Ligand | BDBM50023142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49566 |
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| IC50 | 0.200000±n/a nM |
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| Citation |  Bock, MG; DiPardo, RM; Evans, BE; Rittle, KE; Veber, DF; Freidinger, RM; Chang, RS; Lotti, VJ Cholecystokinin antagonists. Synthesis and biological evaluation of 4-substituted 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepines. J Med Chem31:176-81 (1988) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cholecystokinin receptor type A |
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| Name: | Cholecystokinin receptor type A |
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| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49676.37 |
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| Organism: | RAT |
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| Description: | Cholecystokinin central 0 RAT::P30551 |
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| Residue: | 444 |
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| Sequence: | MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQI
LLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLK
DFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAAT
WCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVM
VVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQL
SSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAE
KHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEE
DGRTIRALLSRYSYSHMSTSAPPP
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| BDBM50023142 |
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| n/a |
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| Name | BDBM50023142 |
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| Synonyms: | 1H-Indole-2-carboxylic acid [6-(2-fluoro-phenyl)-1-methyl-4H-2,3,5,10b-tetraaza-benzo[e]azulen-4-yl]-amide(0.2EtOAc) | CHEMBL53907 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H19FN6O |
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| Mol. Mass. | 450.4671 |
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| SMILES | Cc1nnc2C(NC(=O)c3cc4ccccc4[nH]3)N=C(c3ccccc3F)c3ccccc3-n12 |t:20| |
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| Structure | 
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