| Reaction Details |
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 | Report a problem with these data |
| Target | D-amino-acid oxidase |
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| Ligand | BDBM50008990 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1768986 (CHEMBL4221098) |
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| Kd | 4430±n/a nM |
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| Citation |  Szilágyi, B; Kovács, P; Ferenczy, GG; Rácz, A; Németh, K; Visy, J; Szabó, P; Ilas, J; Balogh, GT; Monostory, K; Vincze, I; Tábi, T; Szök?, É; Keser?, GM Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors. Bioorg Med Chem26:1579-1587 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-amino-acid oxidase |
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| Name: | D-amino-acid oxidase |
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| Synonyms: | D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG |
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| Type: | Flavoprotein |
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| Mol. Mass.: | 39338.01 |
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| Organism: | Sus scrofa (pig) |
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| Description: | Homodimer. |
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| Residue: | 347 |
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| Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPS
NPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPR
ELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIIN
CTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGG
TFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGS
SNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
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| BDBM50008990 |
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| n/a |
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| Name | BDBM50008990 |
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| Synonyms: | 1,2-Dihydro-indazol-3-one | 1H-indazol-3-ol | CHEMBL276725 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H6N2O |
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| Mol. Mass. | 134.1353 |
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| SMILES | O=c1[nH][nH]c2ccccc12 |
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| Structure | 
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