| Reaction Details |
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 | Report a problem with these data |
| Target | 4,4'-diapophytoene synthase |
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| Ligand | BDBM50460684 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1770082 (CHEMBL4222194) |
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| Ki | 7870±n/a nM |
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| Citation |  Banu, S; Bollu, R; Naseema, M; Gomedhika, PM; Nagarapu, L; Sirisha, K; Kumar, CG; Gundasw, SK A novel templates of piperazinyl-1,2-dihydroquinoline-3-carboxylates: Synthesis, anti-microbial evaluation and molecular docking studies. Bioorg Med Chem Lett28:1166-1170 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 4,4'-diapophytoene synthase |
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| Name: | 4,4'-diapophytoene synthase |
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| Synonyms: | CRTM_STAAU | Dehydrosqualene synthase | crtM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34309.10 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_1352846 |
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| Residue: | 287 |
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| Sequence: | MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFL
NQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMF
ETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENE
RIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPI
IELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKYHRI
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| BDBM50460684 |
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| n/a |
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| Name | BDBM50460684 |
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| Synonyms: | CHEMBL4227311 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24FN3O3 |
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| Mol. Mass. | 409.4534 |
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| SMILES | CCOC(=O)c1c(N2CCN(CC2)c2ccccc2F)c2ccccc2n(C)c1=O |
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| Structure | 
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