| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50461707 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1771904 (CHEMBL4224016) |
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| Ki | 460±n/a nM |
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| Citation |  Amato, GS; Manke, A; Harris, DL; Wiethe, RW; Vasukuttan, V; Snyder, RW; Lefever, TW; Cortes, R; Zhang, Y; Wang, S; Runyon, SP; Maitra, R Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor. J Med Chem61:4370-4385 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50461707 |
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| n/a |
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| Name | BDBM50461707 |
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| Synonyms: | CHEMBL4225446 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H23Cl2N7 |
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| Mol. Mass. | 540.446 |
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| SMILES | Clc1ccc(cc1)-n1c(nc2c(ncnc12)N1CCN(CC1)C(C#N)c1ccccc1)-c1ccccc1Cl |
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| Structure | 
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