| Reaction Details |
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 | Report a problem with these data |
| Target | C5a anaphylatoxin chemotactic receptor 1 |
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| Ligand | BDBM50462086 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1772749 (CHEMBL4229741) |
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| IC50 | 2.0±n/a nM |
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| Citation |  Iyer, A; Xu, W; Reid, RC; Fairlie, DP Chemical Approaches to Modulating Complement-Mediated Diseases. J Med Chem61:3253-3276 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C5a anaphylatoxin chemotactic receptor 1 |
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| Name: | C5a anaphylatoxin chemotactic receptor 1 |
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| Synonyms: | C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39347.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21730 |
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| Residue: | 350 |
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| Sequence: | MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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| BDBM50462086 |
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| n/a |
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| Name | BDBM50462086 |
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| Synonyms: | CHEMBL1628668 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H36N2O2 |
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| Mol. Mass. | 456.619 |
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| SMILES | COc1ccc2CCCC(C(=O)N(Cc3ccc(cc3)N(C)C)c3ccc(cc3)C(C)C)c2c1 |
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| Structure | 
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