| Reaction Details |
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 | Report a problem with these data |
| Target | Complement factor D |
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| Ligand | BDBM50462091 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1772732 (CHEMBL4229724) |
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| IC50 | 100±n/a nM |
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| Citation |  Iyer, A; Xu, W; Reid, RC; Fairlie, DP Chemical Approaches to Modulating Complement-Mediated Diseases. J Med Chem61:3253-3276 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Complement factor D |
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| Name: | Complement factor D |
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| Synonyms: | Adipsin | C3 convertase activator | CFAD_HUMAN | CFD | DF | PFD | Properdin factor D |
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| Type: | Protein |
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| Mol. Mass.: | 27039.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00746 |
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| Residue: | 253 |
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| Sequence: | MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQW
VLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQL
SEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCN
RRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTR
VASYAAWIDSVLA
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| BDBM50462091 |
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| n/a |
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| Name | BDBM50462091 |
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| Synonyms: | CHEMBL4241950 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14O8 |
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| Mol. Mass. | 358.299 |
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| SMILES | CC(=O)Oc1ccc(cc1C(O)=O)-c1ccc(OC(C)=O)c(c1)C(O)=O |
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| Structure | 
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