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TargetC5a anaphylatoxin chemotactic receptor 1
LigandBDBM50462093
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1772756 (CHEMBL4229748)
IC50 1.000000±n/a nM
Citation Iyer, AXu, WReid, RCFairlie, DP Chemical Approaches to Modulating Complement-Mediated Diseases. J Med Chem61:3253-3276 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C5a anaphylatoxin chemotactic receptor 1
Name:C5a anaphylatoxin chemotactic receptor 1
Synonyms:C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88
Type:Enzyme
Mol. Mass.:39347.68
Organism:Homo sapiens (Human)
Description:P21730
Residue:350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVW
VTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNM
YASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREE
YFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKT
LKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIY
VVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
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  Blast E-value cutoff:
BDBM50462093
n/a
NameBDBM50462093
Synonyms:CHEMBL4245250
TypeSmall organic molecule
Emp. Form.C35H33N3O4
Mol. Mass.559.6542
SMILESCCCCn1c(nc(c1N(Cc1ccc2OCOc2c1)Cc1ccc2OCOc2c1)-c1ccccc1)-c1ccccc1
Structure
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