| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50462123 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1772772 (CHEMBL4229764) |
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| Ki | 0.300000±n/a nM |
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| Citation |  Ramesh, R; Reddy, DS Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds. J Med Chem61:3779-3798 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50462123 |
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| n/a |
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| Name | BDBM50462123 |
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| Synonyms: | CHEMBL4250984 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H29NSi |
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| Mol. Mass. | 287.5151 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6]-[#7]-1-[#6]-[#6][Si;v4]2([#6]-[#6]-[#6]-c3ccccc23)[#6]-[#6]-1 |
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| Structure | 
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