| Reaction Details |
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 | Report a problem with these data |
| Target | Transient receptor potential cation channel subfamily V member 4 |
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| Ligand | BDBM50463443 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1778240 (CHEMBL4235232) |
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| EC50 | 18000±n/a nM |
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| Citation |  Lopatriello, A; Caprioglio, D; Minassi, A; Schiano Moriello, A; Formisano, C; De Petrocellis, L; Appendino, G; Taglialatela-Scafati, O Iodine-mediated cyclization of cannabigerol (CBG) expands the cannabinoid biological and chemical space. Bioorg Med Chem26:4532-4536 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transient receptor potential cation channel subfamily V member 4 |
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| Name: | Transient receptor potential cation channel subfamily V member 4 |
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| Synonyms: | TRPV4_RAT | Trpv4 | Vanilloid receptor | Vroac |
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| Type: | PROTEIN |
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| Mol. Mass.: | 98016.72 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1514408 |
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| Residue: | 871 |
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| Sequence: | MADPGDGPRAAPGDVAEPPGDESGTSGGEAFPLSSLANLFEGEEGSSSLSPVDASRPAGP
GDGRPNLRMKFQGAFRKGVPNPIDLLESTLYESSVVPGPKKAPMDSLFDYGTYRHHPSDN
KRWRRKVVEKQPQSPKAPAPQPPPILKVFNRPILFDIVSRGSTADLDGLLSYLLTHKKRL
TDEEFREPSTGKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQT
ALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHI
VNYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCSRLFPDS
NLETVLNNDGLSPLMMAAKTGKIGVFQHIIRREVTDEDTRHLSRKFKDWAYGPVYSSLYD
LSSLDTCGEEVSVLEILVYNSKIENRHEMLAVEPINELLRDKWRKFGAVSFYINVVSYLC
AMVIFTLTAYYQPLEGTPPYPYRTTVDYLRLAGEVITLLTGVLFFFTSIKDLFMKKCPGV
NSLFVDGSFQLLYFIYSVLVVVSAALYLAGIEAYLAVMVFALVLGWMNALYFTRGLKLTG
TYSIMIQKILFKDLFRFLLVYLLFMIGYASALVTLLNPCTNMKVCNEDQSNCTVPSYPAC
RDSETFSAFLLDLFKLTIGMGDLEMLSSAKYPVVFILLLVTYIILTFVLLLNMLIALMGE
TVGQVSKESKHIWKLQWATTILDIERSFPVFLRKAFRSGEMVTVGKSSDGTPDRRWCFRV
DEVNWSHWNQNLGIINEDPGKSEIYQYYGFSHTMGRLRRDRWSSVVPRVVELNKNSGTDE
VVVPLDNLGNPNCDGHQQGYAPKWRAEDAPL
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| BDBM50463443 |
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| n/a |
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| Name | BDBM50463443 |
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| Synonyms: | CHEMBL4241477 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H40O2 |
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| Mol. Mass. | 408.616 |
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| SMILES | CCCCCc1cc(O)c2CCC(C)(CCCC(C)(C)c3ccc(C)cc3)Oc2c1 |
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| Structure | 
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