| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 7 |
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| Ligand | BDBM50463582 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1778811 (CHEMBL4235803) |
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| IC50 | >30000±n/a nM |
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| Citation |  Tawaraishi, T; Sakauchi, N; Hidaka, K; Yoshikawa, K; Okui, T; Kuno, H; Chisaki, I; Aso, K Identification of a novel series of potent and selective CCR6 inhibitors as biological probes. Bioorg Med Chem Lett28:3067-3072 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 7 |
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| Name: | C-C chemokine receptor type 7 |
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| Synonyms: | CCR7 | CCR7_HUMAN | CMKBR7 | EBI1 | EVI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42885.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_338819 |
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| Residue: | 378 |
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| Sequence: | MDLGKPMKSVLVVALLVIFQVCLCQDEVTDDYIGDNTTVDYTLFESLCSKKDVRNFKAWF
LPIMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPFWAYSAAK
SWVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCV
GIWILATVLSIPELLYSDLQRSSSEQAMRCSLITEHVEAFITIQVAQMVIGFLVPLLAMS
FCYLVIIRTLLQARNFERNKAIKVIIAVVVVFIVFQLPYNGVVLAQTVANFNITSSTCEL
SKQLNIAYDVTYSLACVRCCVNPFLYAFIGVKFRNDLFKLFKDLGCLSQEQLRQWSSCRH
IRRSSMSVEAETTTTFSP
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| BDBM50463582 |
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| n/a |
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| Name | BDBM50463582 |
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| Synonyms: | CHEMBL4245957 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N4O2S |
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| Mol. Mass. | 356.442 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N |
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| Structure | 
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