| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
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| Ligand | BDBM50464430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1780513 (CHEMBL4252030) |
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| IC50 | 3448±n/a nM |
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| Citation |  Taha, M; Irshad, M; Imran, S; Chigurupati, S; Selvaraj, M; Rahim, F; Ismail, NH; Nawaz, F; Khan, KM Synthesis of piperazine sulfonamide analogs as diabetic-II inhibitors and their molecular docking study. Eur J Med Chem141:530-537 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic alpha-amylase |
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| Name: | Pancreatic alpha-amylase |
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| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase |
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| Type: | Protein |
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| Mol. Mass.: | 57088.07 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00690 |
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| Residue: | 511 |
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| Sequence: | MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPP
NENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGS
GAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGL
LDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAG
SRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWG
FMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWA
RNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQP
FANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGI
KVYVSSDGTAQFSISNSAEDPFIAIHAESKL
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| BDBM50464430 |
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| n/a |
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| Name | BDBM50464430 |
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| Synonyms: | CHEMBL4293503 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21BrN2O2S |
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| Mol. Mass. | 409.341 |
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| SMILES | Cc1ccc(CN2CCN(CC2)S(=O)(=O)c2cccc(Br)c2)cc1 |
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| Structure | 
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