| Reaction Details |
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 | Report a problem with these data |
| Target | Anthranilate--CoA ligase |
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| Ligand | BDBM50324670 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1788565 (CHEMBL4260299) |
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| Ki | 88±n/a nM |
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| Citation |  Soukarieh, F; Williams, P; Stocks, MJ; Cámara, M Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. J Med Chem61:10385-10402 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Anthranilate--CoA ligase |
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| Name: | Anthranilate--CoA ligase |
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| Synonyms: | Anthranilyl-CoA synthetase PqsA (PqsA) | PQSA_PSEAE | pqsA |
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| Type: | Protein |
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| Mol. Mass.: | 56603.82 |
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| Organism: | Pseudomonas aeruginosa (Gram- Bacteria) |
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| Description: | n/a |
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| Residue: | 517 |
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| Sequence: | MSTLANLTEVLFRLDFDPDTAVYHYRGQTLSRLQCRTYILSQASQLARLLKPGDRVVLAL
NDSPSLACLFLACIAVGAIPAVINPKSREQALADIAADCQASLVVREADAPSLSGPLAPL
TLRAAAGRPLLDDFSLDALVGPADLDWSAFHRQDPAAACFLQYTSGSTGAPKGVMHSLRN
TLGFCRAFATELLALQAGDRLYSIPKMFFGYGMGNSLFFPWFSGASALLDDTWPSPERVL
ENLVAFRPRVLFGVPAIYASLRPQARELLSSVRLAFSAGSPLPRGEFEFWAAHGLEICDG
IGATEVGHVFLANRPGQARADSTGLPLPGYECRLVDREGHTIEEAGRQGVLLVRGPGLSP
GYWRASEEQQARFAGGWYRTGDLFERDESGAYRHCGREDDLFKVNGRWVVPTQVEQAICR
HLPEVSEAVLVPTCRLHDGLRPTLFVTLATPLDDNQILLAQRIDQHLAEQIPSHMLPSQL
HVLPALPRNDNGKLARAELRHLADTLYHDNLPEERAC
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| BDBM50324670 |
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| n/a |
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| Name | BDBM50324670 |
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| Synonyms: | ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl 2-hydroxybenzoylsulfamate | 5'-O-(N-(2-hydroxybenzoyl)sulfamoyl)adenosine | 5'-O-[N-(salicyl)-sulfamoyl]-adenosine | 5'-O-[N-(salicyl)sulfamoyl] adenosine | 5'-O-[N-(salicyl)sulfamoyl]adenosine | CHEMBL371502 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18N6O8S |
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| Mol. Mass. | 466.425 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COS(=O)(=O)NC(=O)c2ccccc2O)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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