| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxoacyl-ACP synthase |
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| Ligand | BDBM23570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1788585 (CHEMBL4260319) |
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| IC50 | 65000±n/a nM |
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| Citation |  Soukarieh, F; Williams, P; Stocks, MJ; Cámara, M Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. J Med Chem61:10385-10402 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxoacyl-ACP synthase |
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| Name: | 3-oxoacyl-ACP synthase |
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| Synonyms: | 2-heptyl-4(1H)-quinolone synthase PqsD | 3-oxoacyl-(Acyl carrier protein) synthase III | 3-oxoacyl-ACP synthase | ERS445055_04170 | PA8380_44470 | PAE221_04722 | PQB biosynthetic 3-oxoacyl-[acyl-carrier-protein] synthase III | YQ19_24710 | pqsD |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36357.84 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_109728 |
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| Residue: | 337 |
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| Sequence: | MGNPILAGLGFSLPKRQVSNHDLVGRINTSDEFIVERTGVRTRYHVEPEQAVSALMVPAA
RQAIEAAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLGLRHIPVLDIRAQCSGLLYGL
QMARGQILAGLARHVLVVCGEVLSKRMDCSDRGRNLSILLGDGAGAVVVSAGESLDDGLL
DLRLGADGNYFDLLMTAAPGSASPTFLDENVLREGGGEFLMRGRPMFEHASQTLVRIAGE
MLAAHELTLDDIDHVICHQPNLRILDAVQEQLGIPQHKFAVTVDRLGNMASASTPVTLAM
FWPDIQPGQRVLVLTYGSGATWGAALYRKPEEVNRPC
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| BDBM23570 |
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| n/a |
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| Name | BDBM23570 |
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| Synonyms: | 2-{[4-bromo-3-(diethylsulfamoyl)benzene]amido}benzoic acid | Diethylsulfonamide Derivative, 13a |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19BrN2O5S |
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| Mol. Mass. | 455.323 |
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| SMILES | CCN(CC)S(=O)(=O)c1cc(ccc1Br)C(=O)Nc1ccccc1C(O)=O |
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| Structure | 
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