| Reaction Details |
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 | Report a problem with these data |
| Target | Chaperone SurA |
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| Ligand | BDBM50467858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1797153 (CHEMBL4269270) |
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| IC50 | 2660±n/a nM |
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| Citation |  Bell, EW; Zheng, EJ; Ryno, LM Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques. Bioorg Med Chem Lett28:3540-3548 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chaperone SurA |
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| Name: | Chaperone SurA |
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| Synonyms: | 5.2.1.8 | Chaperone SurA | PPIase SurA | Peptidyl-prolyl cis-trans isomerase SurA | Rotamase SurA | SURA_ECOLI | Survival protein A | surA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47285.20 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_117815 |
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| Residue: | 428 |
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| Sequence: | MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQL
PDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAY
DGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHIL
IPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELP
GIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTD
EQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRL
NKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRAS
AYVKILSN
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| BDBM50467858 |
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| n/a |
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| Name | BDBM50467858 |
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| Synonyms: | CHEMBL4282968 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H61N9O12 |
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| Mol. Mass. | 920.0189 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(O)=O |r| |
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| Structure | 
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