| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 11B1, mitochondrial |
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| Ligand | BDBM50026000 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196 |
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| IC50 | >100000±n/a nM |
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| Citation |  Cross, PE; Dickinson, RP; Parry, MJ; Randall, MJ Selective thromboxane synthetase inhibitors. 1. 1-[(Aryloxy)alkyl]-1H-imidazoles. J Med Chem28:1427-32 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 11B1, mitochondrial |
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| Name: | Cytochrome P450 11B1, mitochondrial |
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| Synonyms: | C11B1_RAT | Cyp11b-1 | Cyp11b1 | Cytochrome P450 11B | Cytochrome P450 11B1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57478.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1475489 |
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| Residue: | 499 |
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| Sequence: | MALRVTADVWLARPWQCLHRTRALGTTAKVAPKTLKPFEAIPQYSRNKWLKMIQILREQG
QENLHLEMHQAFQELGPIFRHSAGGAQIVSVMLPEDAEKLHQVESILPHRMPLEPWVAHR
ELRGLRRGVFLLNGADWRFNRLQLNPNMLSPKAIQSFVPFVDVVARDFVENLKKRMLENV
HGSMSINIQSNMFNYTMEASHFVISGERLGLTGHDLKPESVTFTHALHSMFKSTTQLMFL
PKSLTRWTSTRVWKEHFDSWDIISEYVTKCIKNVYRELAEGRQQSWSVISEMVAQSTLSM
DAIHANSMELIAGSVDTTAISLVMTLFELARNPDVQQALRQESLAAEASIVANPQKAMSD
LPLLRAALKETLRLYPVGSFVERIVHSDLVLQNYHVPAGTFVIIYLYSMGRNPAVFPRPE
RYMPQRWLERKRSFQHLAFGFGVRQCLGRRLAEVEMLLLLHHMLKTFQVETLRQEDMQMV
FRFLLMPSSSPFLTFRPVS
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| BDBM50026000 |
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| n/a |
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| Name | BDBM50026000 |
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| Synonyms: | 3-(2-Imidazol-1-yl-ethoxy)-benzoic acid | CHEMBL33407 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N2O3 |
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| Mol. Mass. | 232.2353 |
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| SMILES | OC(=O)c1cccc(OCCn2ccnc2)c1 |
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| Structure | 
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