| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Thiosulfate sulfurtransferase |
|---|
| Ligand | BDBM50370232 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1797977 (CHEMBL4270094) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Kunkle, T; Abdeen, S; Salim, N; Ray, AM; Stevens, M; Ambrose, AJ; Victorino, J; Park, Y; Hoang, QQ; Chapman, E; Johnson, SM Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. J Med Chem61:10651-10664 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Thiosulfate sulfurtransferase |
|---|
| Name: | Thiosulfate sulfurtransferase |
|---|
| Synonyms: | 2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33432.06 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_118080 |
|---|
| Residue: | 297 |
|---|
| Sequence: | MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFD
IEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFG
HRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLV
DSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDL
SQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
|
|
|
|---|
| BDBM50370232 |
|---|
| n/a |
|---|
| Name | BDBM50370232 |
|---|
| Synonyms: | BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampicin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C43H58N4O12 |
|---|
| Mol. Mass. | 822.9402 |
|---|
| SMILES | CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)c(\C=N\N4CCN(C)CC4)c(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C |r,c:33,t:3,35| |
|---|
| Structure | 
|
|---|
Search and Browse
