| Reaction Details |
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 | Report a problem with these data |
| Target | Quorum-sensing transcriptional repressor QscR |
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| Ligand | BDBM50468424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1799502 (CHEMBL4271794) |
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| EC50 | 3455±n/a nM |
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| Citation |  Boursier, ME; Manson, DE; Combs, JB; Blackwell, HE A comparative study of non-native N-acyl l-homoserine lactone analogs in two Pseudomonas aeruginosa quorum sensing receptors that share a common native ligand yet inversely regulate virulence. Bioorg Med Chem26:5336-5342 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Quorum-sensing transcriptional repressor QscR |
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| Name: | Quorum-sensing transcriptional repressor QscR |
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| Synonyms: | PhzR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27251.33 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_466843 |
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| Residue: | 237 |
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| Sequence: | MHDEREGYLEILSRITTEEEFFSLVLEICGNYGFEFFSFGARAPFPLTAPKYHFLSNYPG
EWKSRYISEDYTSIDPIVRHGLLEYTPLIWNGEDFQENRFFWEEALHHGIRHGWSIPVRG
KYGLISMLSLVRSSESIAATEILEKESFLLWITSMLQATFGDLLAPRIVPESNVRLTARE
TEMLKWTAVGKTYGEIGLILSIDQRTVKFHIVNAMRKLNSSNKAEATMKAYAIGLLN
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| BDBM50468424 |
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| n/a |
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| Name | BDBM50468424 |
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| Synonyms: | CHEMBL4287516 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H29NO4 |
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| Mol. Mass. | 299.4058 |
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| SMILES | CCCCCCCCCC(=O)CC(=O)N[C@H]1CCO[C@@H]1O |r| |
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| Structure | 
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