| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
|---|
| Ligand | BDBM50065628 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1800085 (CHEMBL4272377) |
|---|
| IC50 | 20±n/a nM |
|---|
| Citation |  Juillerat-Jeanneret, L; Aubert, JD; Mikulic, J; Golshayan, D Fibrogenic Disorders in Human Diseases: From Inflammation to Organ Dysfunction. J Med Chem61:9811-9840 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 2 |
|---|
| Name: | Sphingosine 1-phosphate receptor 2 |
|---|
| Synonyms: | Edg5 | S1PR2_RAT | S1pr2 | Sphingosine 1-phosphate receptor 2 (S1P2) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 38749.58 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P47752 |
|---|
| Residue: | 352 |
|---|
| Sequence: | MGGLYSEYLNPEKVQEHYNYTKETLDMQETPSRKVASAFIIILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASV
FSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACS
TVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLG
VFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVL
RPLLCWRQGKGATGRRGGNPGHRLLPLRSSSSLERGLHMPTSPTFLEGNTVV
|
|
|
|---|
| BDBM50065628 |
|---|
| n/a |
|---|
| Name | BDBM50065628 |
|---|
| Synonyms: | CHEMBL1368758 | US9663511, Compound JTE013 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19Cl2N7O |
|---|
| Mol. Mass. | 408.285 |
|---|
| SMILES | CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(Cl)c2)nc2n(C)nc(C)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
