| Reaction Details |
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 | Report a problem with these data |
| Target | Protein kinase C zeta type |
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| Ligand | BDBM6760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_162373 (CHEMBL769180) |
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| IC50 | 60±n/a nM |
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| Citation |  TBA Bioorg Med Chem Lett4:1333-1338 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein kinase C zeta type |
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| Name: | Protein kinase C zeta type |
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| Synonyms: | KPCZ_RAT | Pkcz | Prkcz | Protein kinase C (PKC) | Protein kinase C zeta type | nPKC-zeta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 67722.31 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_104731 |
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| Residue: | 592 |
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| Sequence: | MPSRTDPKMDRSGGRVRLKAHYGGDILITSVDPTTTFQDLCEEVRDMCGLHQQHPLTLKW
VDSEGDPCTVSSQMELEEAFRLACQGRDEVLIIHVFPSIPEQPGMPCPGEDKSIYRRGAR
RWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHVLVPLTC
RRHMDSVMPSQEPPVDDKNDGVDLPSEETDGIAYISSSRKHDNIKDDSEDLKPVIDGVDG
IKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTE
KHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEI
CIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAP
EILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRF
LSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQIT
DDYGLDNFDTQFTSEPVQLTPDDEDVIKRIDQSEFEGFEYINPLLLSAEESV
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| BDBM6760 |
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| n/a |
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| Name | BDBM6760 |
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| Synonyms: | (+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-16-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C27H21N3O5 |
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| Mol. Mass. | 467.4727 |
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| SMILES | COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| |
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| Structure | 
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